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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1974 1
1975 1
1977 1
1979 2
1980 1
1984 2
1985 3
1986 3
1987 1
1988 1
1989 1
1991 2
1992 2
1993 3
1994 2
1995 3
1996 7
1997 4
1998 3
1999 7
2000 7
2001 8
2002 11
2003 22
2004 15
2005 9
2006 20
2007 25
2008 15
2009 17
2010 27
2011 23
2012 23
2013 23
2014 29
2015 22
2016 29
2017 16
2018 31
2019 23
2020 28
2021 26
2022 28
2023 26
2024 19

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521 results

Results by year

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Page 1
The relevance of daylight for humans.
Wirz-Justice A, Skene DJ, Münch M. Wirz-Justice A, et al. Biochem Pharmacol. 2021 Sep;191:114304. doi: 10.1016/j.bcp.2020.114304. Epub 2020 Oct 28. Biochem Pharmacol. 2021. PMID: 33129807 Free article. Review.
Daylight is ubiquitous and is crucial for mammalian vision as well as for non-visual input to the brain via the intrinsically photosensitive retinal ganglion cells (ipRGCs) that express the photopigment melanopsin. The ipRGCs project to the circadian clock in the suprachia …
Daylight is ubiquitous and is crucial for mammalian vision as well as for non-visual input to the brain via the intrinsically photosensitive …
Photoperiodic flowering: time measurement mechanisms in leaves.
Song YH, Shim JS, Kinmonth-Schultz HA, Imaizumi T. Song YH, et al. Annu Rev Plant Biol. 2015;66:441-64. doi: 10.1146/annurev-arplant-043014-115555. Epub 2014 Dec 12. Annu Rev Plant Biol. 2015. PMID: 25534513 Free PMC article. Review.
Many plants use information about changing day length (photoperiod) to align their flowering time with seasonal changes to increase reproductive success. A mechanism for photoperiodic time measurement is present in leaves, and the day-length-specific induction of th …
Many plants use information about changing day length (photoperiod) to align their flowering time with seasonal changes to increase r …
The lunar cycle: effects on human and animal behavior and physiology.
Zimecki M. Zimecki M. Postepy Hig Med Dosw (Online). 2006;60:1-7. Postepy Hig Med Dosw (Online). 2006. PMID: 16407788 Free article. Review.
Animal studies revealed that the lunar cycle may affect hormonal changes early in phylogenesis (insects). In fish the lunar clock influences reproduction and involves the hypothalamus-pituitary-gonadal axis. ...It is suggested that melatonin and endogenous steroids may med …
Animal studies revealed that the lunar cycle may affect hormonal changes early in phylogenesis (insects). In fish the lunar clock inf …
MYC2: the master in action.
Kazan K, Manners JM. Kazan K, et al. Mol Plant. 2013 May;6(3):686-703. doi: 10.1093/mp/sss128. Epub 2012 Nov 9. Mol Plant. 2013. PMID: 23142764 Free article. Review.
MYC2 coordinates JA-mediated defense responses by antagonistically regulating two different branches of the JA signaling pathway that determine resistance to pests and pathogens, respectively. MYC2 is required for induced systemic resistance (ISR) triggered by beneficial s …
MYC2 coordinates JA-mediated defense responses by antagonistically regulating two different branches of the JA signaling pathway that determ …
Potential circadian effects on translational failure for neuroprotection.
Esposito E, Li W, T Mandeville E, Park JH, Şencan I, Guo S, Shi J, Lan J, Lee J, Hayakawa K, Sakadžić S, Ji X, Lo EH. Esposito E, et al. Nature. 2020 Jun;582(7812):395-398. doi: 10.1038/s41586-020-2348-z. Epub 2020 Jun 3. Nature. 2020. PMID: 32494010 Free PMC article.
We tested three independent neuroprotective approaches-normobaric hyperoxia, the free radical scavenger alpha-phenyl-butyl-tert-nitrone (alphaPBN), and the N-methyl-D-aspartic acid (NMDA) antagonist MK801-in mouse and rat models of focal cerebral ischaemia. All three treatments r …
We tested three independent neuroprotective approaches-normobaric hyperoxia, the free radical scavenger alpha-phenyl-butyl-tert-nitrone (alp …
MitoTimer: a novel tool for monitoring mitochondrial turnover.
Hernandez G, Thornton C, Stotland A, Lui D, Sin J, Ramil J, Magee N, Andres A, Quarato G, Carreira RS, Sayen MR, Wolkowicz R, Gottlieb RA. Hernandez G, et al. Autophagy. 2013 Nov 1;9(11):1852-61. doi: 10.4161/auto.26501. Epub 2013 Oct 11. Autophagy. 2013. PMID: 24128932 Free PMC article.
Fluorescent Timer, or DsRed1-E5, is a mutant of the red fluorescent protein, dsRed, in which fluorescence shifts over time from green to red as the protein matures. This molecular clock gives temporal and spatial information on protein turnover. ...The extent of new …
Fluorescent Timer, or DsRed1-E5, is a mutant of the red fluorescent protein, dsRed, in which fluorescence shifts over time from green …
Neurons as oscillators.
Stiefel KM, Ermentrout GB. Stiefel KM, et al. J Neurophysiol. 2016 Dec 1;116(6):2950-2960. doi: 10.1152/jn.00525.2015. Epub 2016 Sep 28. J Neurophysiol. 2016. PMID: 27683887 Free PMC article. Review.
Next, we show how the PRC can be related to a number of common measures used to quantify neuronal firing, such as the spike-triggered average and the peristimulus histogram. We further show that the response of a neuron to correlated inputs depends on the shape of the PRC. …
Next, we show how the PRC can be related to a number of common measures used to quantify neuronal firing, such as the spike-triggered …
A Time for MYC: Metabolism and Therapy.
Dang CV. Dang CV. Cold Spring Harb Symp Quant Biol. 2016;81:79-83. doi: 10.1101/sqb.2016.81.031153. Epub 2017 Feb 7. Cold Spring Harb Symp Quant Biol. 2016. PMID: 28174256 Review.
Deregulated MYC drives transcriptional imbalance, thereby altering metabolism and disrupting the circadian Bmal1-Clock E-box-dependent transcriptional circuitry. Sustained oncogenic MYC expression drives a constitutive growth program with mammalian target of rapamycin (mTO …
Deregulated MYC drives transcriptional imbalance, thereby altering metabolism and disrupting the circadian Bmal1-Clock E-box-dependen …
Colon: a gateway for chronotherapeutic drug delivery systems.
Patel MM. Patel MM. Expert Opin Drug Deliv. 2015;12(9):1389-95. doi: 10.1517/17425247.2015.1060217. Epub 2015 Jul 8. Expert Opin Drug Deliv. 2015. PMID: 26153223
For the treatment of these diseases, development of a chronotherapeutic drug delivery system (CrDDS), which delivers a defined dose, at a selected time and chosen rate, and to a targeted site is required. Several CrDDSs have been developed by using various strategies (pH-, …
For the treatment of these diseases, development of a chronotherapeutic drug delivery system (CrDDS), which delivers a defined dose, at a se …
The circadian clock and diseases of the skin.
Duan J, Greenberg EN, Karri SS, Andersen B. Duan J, et al. FEBS Lett. 2021 Oct;595(19):2413-2436. doi: 10.1002/1873-3468.14192. Epub 2021 Sep 29. FEBS Lett. 2021. PMID: 34535902 Free PMC article. Review.
Synchronized to the light-dark cycle with a period of around 24 hours, the timing of the circadian clock is set by light-triggering signals sent from the retina to the suprachiasmatic nucleus. ...We illustrate the effect of feeding time on the skin circadian …
Synchronized to the light-dark cycle with a period of around 24 hours, the timing of the circadian clock is set by light-triggerin …
521 results